Nafcillin
TL;DR: Nafcillin (CAS 147-52-4) is a chemical compound with molecular formula C21H22N2O5S and molecular weight 414.12494 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Also Known As: nafcillin, Naphcillin, Nafcilline, Nafcilina, Nallpen
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H22N2O5S |
| Molecular Weight | 414.12494 g/mol |
| XLogP | 2.9 |
| Topological Polar Surface Area (TPSA) | 121.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 414.12494 Da |
| Heavy Atoms | 29 |
| Complexity | 699.0 |
| Solubility | Soluble |
| SMILES | CCOC1=C(C2=CC=CC=C2C=C1)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O |
| InChIKey | GPXLMGHLHQJAGZ-JTDSTZFVSA-N |
Product Description
Applications: Nafcillin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nafcillin (CAS 147-52-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Nafcillin (CAS 147-52-4) has the molecular formula C21H22N2O5S and a molecular weight of 414.12 g/mol. Reported properties include a solubility: Soluble. It is also known as nafcillin and Naphcillin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nafcillin
Property Insights of Nafcillin
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nafcillin. The TPSA of 121.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nafcillin. Following Lipinski's Rule of Five, Nafcillin has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nafcillin?
The CAS number of Nafcillin is 147-52-4.
What is the molecular formula of Nafcillin?
The molecular formula of Nafcillin is C21H22N2O5S.
What is the molecular weight of Nafcillin?
The molecular weight of Nafcillin is 414.12494 g/mol.
What are the applications of Nafcillin?
Nafcillin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nafcillin (CAS 147-52-4) with custom...
Where can I buy Nafcillin?
You can request a quote for Nafcillin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nafcillin?
Yes, CoreyChem provides custom synthesis services for Nafcillin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.