Flumethiazide
TL;DR: Flumethiazide (CAS 148-56-1) is a chemical compound with molecular formula C8H6F3N3O4S2 and molecular weight 328.9752 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1,1-dioxo-6-(trifluoromethyl)-4H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Also Known As: FLUMETHIAZIDE, Ademol, Flumethiazid, Flumetiazid, Fludemil
Application Areas
Top 5 of 11 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H6F3N3O4S2 |
| Molecular Weight | 328.9752 g/mol |
| XLogP | -0.2 |
| Topological Polar Surface Area (TPSA) | 135.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 1 |
| Exact Mass | 328.9752 Da |
| Heavy Atoms | 20 |
| Complexity | 617.0 |
| Solubility | SPARINGLY SOL IN WATER; 50 MG/ML IN BOILING WATER WITH DECOMP; PRACTICALLY INSOL IN ETHYL ACETATE, METHYL ETHYL KETONE, BENZENE, TOLUENE; SOL IN METHANOL, ETHANOL, DIMETHYL FORMAMIDE |
| SMILES | C1=C(C(=CC2=C1NC=NS2(=O)=O)S(=O)(=O)N)C(F)(F)F |
| InChIKey | RGUQWGXAYZNLMI-UHFFFAOYSA-N |
Product Description
Applications: Flumethiazide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Flumethiazide (CAS 148-56-1) has the molecular formula C8H6F3N3O4S2 and a molecular weight of 328.98 g/mol. Reported properties include a solubility: SPARINGLY SOL IN WATER; 50 MG/ML IN BOILING WATER WITH DECOMP; PRACTICALLY INSOL IN ETHYL ACETATE, METHYL ETHYL KETONE, BENZENE, TOLUENE; SOL IN METHANOL, ETHANOL, DIMETHYL FORMAMIDE. Synonyms include FLUMETHIAZIDE and Ademol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Flumethiazide
Property Insights of Flumethiazide
The XLogP value of -0.2 indicates that Flumethiazide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 135.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Flumethiazide. Following Lipinski's Rule of Five, Flumethiazide has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Flumethiazide?
The CAS number of Flumethiazide is 148-56-1.
What is the molecular formula of Flumethiazide?
The molecular formula of Flumethiazide is C8H6F3N3O4S2.
What is the molecular weight of Flumethiazide?
The molecular weight of Flumethiazide is 328.9752 g/mol.
What are the applications of Flumethiazide?
Flumethiazide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Flumethiazide?
You can request a quote for Flumethiazide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Flumethiazide?
Yes, CoreyChem provides custom synthesis services for Flumethiazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.