Doripenem
TL;DR: Doripenem (CAS 148016-81-3) is a chemical compound with molecular formula C15H24N4O6S2 and molecular weight 420.11374 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Also Known As: Doripenem, Doribax, Finibax, Doripenem hydrate, doripenemum
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H24N4O6S2 |
| Molecular Weight | 420.11374 g/mol |
| XLogP | -3.4 |
| Topological Polar Surface Area (TPSA) | 196.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 7 |
| Exact Mass | 420.11374 Da |
| Heavy Atoms | 27 |
| Complexity | 780.0 |
| SMILES | C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)CNS(=O)(=O)N)C(=O)O)[C@@H](C)O |
| InChIKey | AVAACINZEOAHHE-VFZPANTDSA-N |
Chemical Property Profile of Doripenem
Property Insights of Doripenem
The XLogP value of -3.4 indicates that Doripenem is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 196.0 Ų indicates high polarity, suggesting Doripenem may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Doripenem has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Doripenem?
The CAS number of Doripenem is 148016-81-3.
What is the molecular formula of Doripenem?
The molecular formula of Doripenem is C15H24N4O6S2.
What is the molecular weight of Doripenem?
The molecular weight of Doripenem is 420.11374 g/mol.
Where can I buy Doripenem?
You can request a quote for Doripenem directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Doripenem?
Yes, CoreyChem provides custom synthesis services for Doripenem and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.