MK 0927
TL;DR: MK 0927 (CAS 148437-41-6) is a chemical compound with molecular formula C11H19ClN2O4S3 and molecular weight 374.01956 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-(2-methylpropylamino)-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide;hydrochloride
Also Known As: MK 0927, (+-)-isomer of sezolamide, SEZOLAMIDE HYDROCHLORIDE, 4-(2-Methylpropylamino)-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide;hydrochloride, 4-(isobutylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C11H19ClN2O4S3 |
| Molecular Weight | 374.01956 g/mol |
| XLogP | 1.2814 |
| Topological Polar Surface Area (TPSA) | 151.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 374.01956 Da |
| Heavy Atoms | 21 |
| Complexity | 547.0 |
| SMILES | CC(C)CNC1CCS(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N.Cl |
| InChIKey | VYZDSLFBCSLIEA-UHFFFAOYSA-N |
Chemical Property Profile of MK 0927
Property Insights of MK 0927
The XLogP value of 1.2814 suggests moderate lipophilicity, balancing water solubility and membrane permeability for MK 0927. The TPSA of 151.0 Ų indicates high polarity, suggesting MK 0927 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, MK 0927 has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of MK 0927?
The CAS number of MK 0927 is 148437-41-6.
What is the molecular formula of MK 0927?
The molecular formula of MK 0927 is C11H19ClN2O4S3.
What is the molecular weight of MK 0927?
The molecular weight of MK 0927 is 374.01956 g/mol.
Where can I buy MK 0927?
You can request a quote for MK 0927 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for MK 0927?
Yes, CoreyChem provides custom synthesis services for MK 0927 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.