Pitavastatin lactone
TL;DR: Pitavastatin lactone (CAS 148967-81-1) is a chemical compound with molecular formula C25H22FNO3 and molecular weight 403.1584 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(4R,6S)-6-[(E)-2-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]ethenyl]-4-hydroxyoxan-2-one
Also Known As: Pitavastatin Lactone, Nisvastatin, Itavastatin Lactone, NK-104 (lactone), Pitavastatin Impurity 4
Technical Specifications
| Molecular Formula | C25H22FNO3 |
| Molecular Weight | 403.1584 g/mol |
| XLogP | 4.3 |
| Topological Polar Surface Area (TPSA) | 59.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 403.1584 Da |
| Heavy Atoms | 30 |
| Complexity | 642.0 |
| SMILES | C1CC1C2=NC3=CC=CC=C3C(=C2/C=C/[C@@H]4C[C@H](CC(=O)O4)O)C5=CC=C(C=C5)F |
| InChIKey | XJVKVAFYQRWVAJ-MCBHFWOFSA-N |
Chemical Property Profile of Pitavastatin lactone
Property Insights of Pitavastatin lactone
The XLogP value of 4.3 indicates that Pitavastatin lactone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.4 Ų, Pitavastatin lactone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Pitavastatin lactone has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Pitavastatin lactone?
The CAS number of Pitavastatin lactone is 148967-81-1.
What is the molecular formula of Pitavastatin lactone?
The molecular formula of Pitavastatin lactone is C25H22FNO3.
What is the molecular weight of Pitavastatin lactone?
The molecular weight of Pitavastatin lactone is 403.1584 g/mol.
Where can I buy Pitavastatin lactone?
You can request a quote for Pitavastatin lactone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Pitavastatin lactone?
Yes, CoreyChem provides custom synthesis services for Pitavastatin lactone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.