Donepezil Impurity 11
TL;DR: Donepezil Impurity 11 (CAS 149874-81-7) is a chemical compound with molecular formula C25H31NO3 and molecular weight 393.2304 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5,6-dimethoxy-2-[[1-[(3-methylphenyl)methyl]piperidin-4-yl]methyl]-2,3-dihydroinden-1-one
Also Known As: Donepezil Impurity 11, Donepezil Impurity 53, 5,6-dimethoxy-2-[[1-[(3-methylphenyl)methyl]-4-piperidyl]methyl]-2,3-dihydroinden-1-one, 5,6-Dimethoxy-2-[1-(3-methyl-benzyl)-piperidin-4-ylmethyl]-indan-1-one; hydrochloride
Technical Specifications
| Molecular Formula | C25H31NO3 |
| Molecular Weight | 393.2304 g/mol |
| XLogP | 4.6 |
| Topological Polar Surface Area (TPSA) | 38.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 393.2304 Da |
| Heavy Atoms | 29 |
| Complexity | 544.0 |
| SMILES | CC1=CC(=CC=C1)CN2CCC(CC2)CC3CC4=CC(=C(C=C4C3=O)OC)OC |
| InChIKey | QBOHSSFTEGRUFM-UHFFFAOYSA-N |
Chemical Property Profile of Donepezil Impurity 11
Property Insights of Donepezil Impurity 11
The XLogP value of 4.6 indicates that Donepezil Impurity 11 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.8 Ų, Donepezil Impurity 11 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Donepezil Impurity 11 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Donepezil Impurity 11?
The CAS number of Donepezil Impurity 11 is 149874-81-7.
What is the molecular formula of Donepezil Impurity 11?
The molecular formula of Donepezil Impurity 11 is C25H31NO3.
What is the molecular weight of Donepezil Impurity 11?
The molecular weight of Donepezil Impurity 11 is 393.2304 g/mol.
Where can I buy Donepezil Impurity 11?
You can request a quote for Donepezil Impurity 11 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Donepezil Impurity 11?
Yes, CoreyChem provides custom synthesis services for Donepezil Impurity 11 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.