Ezogabine dihydrochloride
TL;DR: Ezogabine dihydrochloride (CAS 150812-13-8) is a chemical compound with molecular formula C16H20Cl2FN3O2 and molecular weight 375.09167 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
ethyl N-[2-amino-4-[(4-fluorophenyl)methylamino]phenyl]carbamate;dihydrochloride
Also Known As: Retigabine Dihydrochloride, Ezogabine Dihydrochloride, Retigabine 2HCl, Retigabine hydrochloride, Retigabine (dihydrochloride)
Technical Specifications
| Molecular Formula | C16H20Cl2FN3O2 |
| Molecular Weight | 375.09167 g/mol |
| XLogP | 4.432 |
| Topological Polar Surface Area (TPSA) | 76.4 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 375.09167 Da |
| Heavy Atoms | 24 |
| Complexity | 348.0 |
| SMILES | CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N.Cl.Cl |
| InChIKey | WSGFOWNASITQHJ-UHFFFAOYSA-N |
Chemical Property Profile of Ezogabine dihydrochloride
Property Insights of Ezogabine dihydrochloride
The XLogP value of 4.432 indicates that Ezogabine dihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Ezogabine dihydrochloride. Following Lipinski's Rule of Five, Ezogabine dihydrochloride has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Ezogabine dihydrochloride?
The CAS number of Ezogabine dihydrochloride is 150812-13-8.
What is the molecular formula of Ezogabine dihydrochloride?
The molecular formula of Ezogabine dihydrochloride is C16H20Cl2FN3O2.
What is the molecular weight of Ezogabine dihydrochloride?
The molecular weight of Ezogabine dihydrochloride is 375.09167 g/mol.
Where can I buy Ezogabine dihydrochloride?
You can request a quote for Ezogabine dihydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Ezogabine dihydrochloride?
Yes, CoreyChem provides custom synthesis services for Ezogabine dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.