![1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole structure](/static/products/1513/151387-66-5.webp)
1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole
TL;DR: 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole (CAS 151387-66-5) is a chemical compound with molecular formula C14H8ClF3N2 and molecular weight 296.0328 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]indole
Also Known As: Bionet2_000810, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole, 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]indole, 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indole, 2H-958
Technical Specifications
| Molecular Formula | C14H8ClF3N2 |
| Molecular Weight | 296.0328 g/mol |
| XLogP | 4.4 |
| Topological Polar Surface Area (TPSA) | 17.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 296.0328 Da |
| Heavy Atoms | 20 |
| Complexity | 350.0 |
| SMILES | C1=CC=C2C(=C1)C=CN2C3=C(C=C(C=N3)C(F)(F)F)Cl |
| InChIKey | VEOFLNFVIDOHEE-UHFFFAOYSA-N |
Chemical Property Profile of 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole
Property Insights of 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole
The XLogP value of 4.4 indicates that 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.8 Ų, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole?
The CAS number of 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole is 151387-66-5.
What is the molecular formula of 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole?
The molecular formula of 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole is C14H8ClF3N2.
What is the molecular weight of 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole?
The molecular weight of 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole is 296.0328 g/mol.
Where can I buy 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole?
You can request a quote for 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole?
Yes, CoreyChem provides custom synthesis services for 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-indole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.