TL;DR: H-Pro-Gln-Arg-Phe-NH2 (CAS 152050-35-6) is a chemical compound with molecular formula C25H39N9O5 and molecular weight 545.30743 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-(pyrrolidine-2-carbonylamino)pentanediamide
Also Known As: H-Pro-Gln-Arg-Phe-NH2, Neuropeptide FF (5-8), H-PQRF-NH2, Pro-Gln-Arg-Phe amide trifluoroacetate salt, Neuropeptide FF (5-8) acetate salt
| Molecular Formula | C25H39N9O5 |
| Molecular Weight | 545.30743 g/mol |
| XLogP | -2.3 |
| Topological Polar Surface Area (TPSA) | 250.0 Ų |
| Hydrogen Bond Donors | 8 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 16 |
| Exact Mass | 545.30743 Da |
| Heavy Atoms | 39 |
| Complexity | 887.0 |
| SMILES | C1CC(NC1)C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC2=CC=CC=C2)C(=O)N |
| InChIKey | VVKYIUFJEDANQO-UHFFFAOYSA-N |
The XLogP value of -2.3 indicates that H-Pro-Gln-Arg-Phe-NH2 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 250.0 Ų indicates high polarity, suggesting H-Pro-Gln-Arg-Phe-NH2 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, H-Pro-Gln-Arg-Phe-NH2 has 8 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
The CAS number of H-Pro-Gln-Arg-Phe-NH2 is 152050-35-6.
The molecular formula of H-Pro-Gln-Arg-Phe-NH2 is C25H39N9O5.
The molecular weight of H-Pro-Gln-Arg-Phe-NH2 is 545.30743 g/mol.
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