2'-Deoxy-5-fluoro-2-thiouridine
TL;DR: 2'-Deoxy-5-fluoro-2-thiouridine (CAS 152310-66-2) is a chemical compound with molecular formula C9H11FN2O4S and molecular weight 262.04236 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one
Also Known As: 2'-Deoxy-5-fluoro-2-thiouridine, 2 -Deoxy-5-fluoro-2-thiouridine, 5-Fluoro-2 -deoxy-2-thiouridine, 4(1H)-Pyrimidinone, 1-(2-deoxy-b-D-erythro-pentofuranosyl)-5-fluoro-2,3-dihydro-2-thioxo-, 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one
Technical Specifications
| Molecular Formula | C9H11FN2O4S |
| Molecular Weight | 262.04236 g/mol |
| XLogP | -0.6 |
| Topological Polar Surface Area (TPSA) | 114.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 262.04236 Da |
| Heavy Atoms | 17 |
| Complexity | 389.0 |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=S)F)CO)O |
| InChIKey | GEXRNCMFMLEAFL-RRKCRQDMSA-N |
Chemical Property Profile of 2'-Deoxy-5-fluoro-2-thiouridine
Property Insights of 2'-Deoxy-5-fluoro-2-thiouridine
The XLogP value of -0.6 indicates that 2'-Deoxy-5-fluoro-2-thiouridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 114.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-Deoxy-5-fluoro-2-thiouridine. Following Lipinski's Rule of Five, 2'-Deoxy-5-fluoro-2-thiouridine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2'-Deoxy-5-fluoro-2-thiouridine?
The CAS number of 2'-Deoxy-5-fluoro-2-thiouridine is 152310-66-2.
What is the molecular formula of 2'-Deoxy-5-fluoro-2-thiouridine?
The molecular formula of 2'-Deoxy-5-fluoro-2-thiouridine is C9H11FN2O4S.
What is the molecular weight of 2'-Deoxy-5-fluoro-2-thiouridine?
The molecular weight of 2'-Deoxy-5-fluoro-2-thiouridine is 262.04236 g/mol.
Where can I buy 2'-Deoxy-5-fluoro-2-thiouridine?
You can request a quote for 2'-Deoxy-5-fluoro-2-thiouridine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2'-Deoxy-5-fluoro-2-thiouridine?
Yes, CoreyChem provides custom synthesis services for 2'-Deoxy-5-fluoro-2-thiouridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.