4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine
TL;DR: 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine (CAS 152491-80-0) is a chemical compound with molecular formula C11H7F4N3 and molecular weight 257.05762 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-(4-fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Also Known As: 4-(4-fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine, ZERO/005640, IDI1_026122, 4-(Trifluoromethyl)-6-(4-fluorophenyl)pyrimidin-2-amine, BRD-K34080074-001-01-6
Technical Specifications
| Molecular Formula | C11H7F4N3 |
| Molecular Weight | 257.05762 g/mol |
| XLogP | 2.5 |
| Topological Polar Surface Area (TPSA) | 51.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 1 |
| Exact Mass | 257.05762 Da |
| Heavy Atoms | 18 |
| Complexity | 276.0 |
| SMILES | C1=CC(=CC=C1C2=CC(=NC(=N2)N)C(F)(F)F)F |
| InChIKey | RTLMOYXIHOTFIH-UHFFFAOYSA-N |
Chemical Property Profile of 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Property Insights of 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine. With a topological polar surface area (TPSA) of 51.8 Ų, 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine?
The CAS number of 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine is 152491-80-0.
What is the molecular formula of 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine?
The molecular formula of 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine is C11H7F4N3.
What is the molecular weight of 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine?
The molecular weight of 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine is 257.05762 g/mol.
Where can I buy 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine?
You can request a quote for 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine?
Yes, CoreyChem provides custom synthesis services for 4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.