PD 145065
TL;DR: PD 145065 (CAS 153049-49-1) is a chemical compound with molecular formula C52H67N7O10 and molecular weight 949.49493 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3S)-3-[[(2S)-2-[[(2R)-2-acetamido-2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)acetyl]amino]-4-methylpentanoyl]amino]-4-[[(2S,3S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Also Known As: PD 145065, endothelin receptor antagonist*pd 145065, SID:134223749, [AC-DBHG16] ENDOTHELIN-1 (16-21), Acetyl-(5H-dibenzyl(a,d)cycloheptene-10,11-dihydroglycine-leucyl-aspartyl-isoleucyl-isoleucyl-tryptophan)
Technical Specifications
| Molecular Formula | C52H67N7O10 |
| Molecular Weight | 949.49493 g/mol |
| XLogP | 6.4 |
| Topological Polar Surface Area (TPSA) | 265.0 Ų |
| Hydrogen Bond Donors | 9 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 23 |
| Exact Mass | 949.49493 Da |
| Heavy Atoms | 69 |
| Complexity | 1770.0 |
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C3C4=CC=CC=C4CCC5=CC=CC=C35)NC(=O)C |
| InChIKey | HRAQSWKGRRUBDJ-OMUAVVNCSA-N |
Chemical Property Profile of PD 145065
Property Insights of PD 145065
The XLogP value of 6.4 indicates that PD 145065 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 265.0 Ų indicates high polarity, suggesting PD 145065 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, PD 145065 has 9 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of PD 145065?
The CAS number of PD 145065 is 153049-49-1.
What is the molecular formula of PD 145065?
The molecular formula of PD 145065 is C52H67N7O10.
What is the molecular weight of PD 145065?
The molecular weight of PD 145065 is 949.49493 g/mol.
Where can I buy PD 145065?
You can request a quote for PD 145065 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for PD 145065?
Yes, CoreyChem provides custom synthesis services for PD 145065 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.