Diclofenac methyl ester
TL;DR: Diclofenac methyl ester (CAS 15307-78-5) is a chemical compound with molecular formula C15H13Cl2NO2 and molecular weight 309.03235 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
methyl 2-[2-(2,6-dichloroanilino)phenyl]acetate
Also Known As: Diclofenac Methyl Ester, Diclofenac, methyl ester, Methyl diclofenac, Diclofenac, Me, Aceclofenac Impurity B
Application Areas
Top 5 of 4 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H13Cl2NO2 |
| Molecular Weight | 309.03235 g/mol |
| XLogP | 4.7 |
| Topological Polar Surface Area (TPSA) | 38.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 309.03235 Da |
| Heavy Atoms | 20 |
| Complexity | 317.0 |
| SMILES | COC(=O)CC1=CC=CC=C1NC2=C(C=CC=C2Cl)Cl |
| InChIKey | VETACGBDFVVKGZ-UHFFFAOYSA-N |
Chemical Property Profile of Diclofenac methyl ester
Property Insights of Diclofenac methyl ester
The XLogP value of 4.7 indicates that Diclofenac methyl ester is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.3 Ų, Diclofenac methyl ester exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Diclofenac methyl ester has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Diclofenac methyl ester?
The CAS number of Diclofenac methyl ester is 15307-78-5.
What is the molecular formula of Diclofenac methyl ester?
The molecular formula of Diclofenac methyl ester is C15H13Cl2NO2.
What is the molecular weight of Diclofenac methyl ester?
The molecular weight of Diclofenac methyl ester is 309.03235 g/mol.
Where can I buy Diclofenac methyl ester?
You can request a quote for Diclofenac methyl ester directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Diclofenac methyl ester?
Yes, CoreyChem provides custom synthesis services for Diclofenac methyl ester and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.