Diclofenac
TL;DR: Diclofenac (CAS 15307-86-5) is a chemical compound with molecular formula C14H11Cl2NO2 and molecular weight 295.0167 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[2-(2,6-dichloroanilino)phenyl]acetic acid
Also Known As: diclofenac, Diclofenac acid, dichlofenac, Diclofenaco, Diclophenac
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H11Cl2NO2 |
| Molecular Weight | 295.0167 g/mol |
| XLogP | 4.4 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 295.0167 Da |
| Heavy Atoms | 19 |
| Complexity | 304.0 |
| Melting Point | 283-285 °C |
| Solubility | 2.37 |
| SMILES | C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl |
| InChIKey | DCOPUUMXTXDBNB-UHFFFAOYSA-N |
Product Description
Applications: Diclofenac is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Diclofenac (CAS 15307-86-5) is a pharmaceutical intermediate with the molecular formula C14H11Cl2NO2 and a molecular weight of 295.02 g/mol. Key physical properties include a solubility: 2.37. Synonyms include diclofenac and Diclofenac acid.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Diclofenac
Property Insights of Diclofenac
The XLogP value of 4.4 indicates that Diclofenac is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.3 Ų, Diclofenac exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Diclofenac has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Diclofenac?
The CAS number of Diclofenac is 15307-86-5.
What is the molecular formula of Diclofenac?
The molecular formula of Diclofenac is C14H11Cl2NO2.
What is the molecular weight of Diclofenac?
The molecular weight of Diclofenac is 295.0167 g/mol.
What are the applications of Diclofenac?
Diclofenac is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Diclofenac?
You can request a quote for Diclofenac directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Diclofenac?
Yes, CoreyChem provides custom synthesis services for Diclofenac and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.