6-alpha-Hydroxy paclitaxel
TL;DR: 6-alpha-Hydroxy paclitaxel (CAS 153212-75-0) is a chemical compound with molecular formula C47H51NO15 and molecular weight 869.32587 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[(1S,2S,4S,7R,8S,9R,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,8,9-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Also Known As: 6-Hydroxytaxol, 6-alpha-Hydroxy paclitaxel, 6-Hydroxypaclitaxel, 6alpha-Hydroxytaxol, 6-Hydroxy paclitaxel
Technical Specifications
| Molecular Formula | C47H51NO15 |
| Molecular Weight | 869.32587 g/mol |
| XLogP | 1.5 |
| Topological Polar Surface Area (TPSA) | 242.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 15 |
| Rotatable Bonds | 14 |
| Exact Mass | 869.32587 Da |
| Heavy Atoms | 63 |
| Complexity | 1830.0 |
| SMILES | CC1=C2[C@H](C(=O)[C@@]3([C@H]([C@@H]([C@@H]4[C@](C3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)O)C)OC(=O)C |
| InChIKey | NDCWHEDPSFRTDA-MJLVFIKCSA-N |
Chemical Property Profile of 6-alpha-Hydroxy paclitaxel
Property Insights of 6-alpha-Hydroxy paclitaxel
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-alpha-Hydroxy paclitaxel. The TPSA of 242.0 Ų indicates high polarity, suggesting 6-alpha-Hydroxy paclitaxel may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 6-alpha-Hydroxy paclitaxel has 5 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of 6-alpha-Hydroxy paclitaxel?
The CAS number of 6-alpha-Hydroxy paclitaxel is 153212-75-0.
What is the molecular formula of 6-alpha-Hydroxy paclitaxel?
The molecular formula of 6-alpha-Hydroxy paclitaxel is C47H51NO15.
What is the molecular weight of 6-alpha-Hydroxy paclitaxel?
The molecular weight of 6-alpha-Hydroxy paclitaxel is 869.32587 g/mol.
Where can I buy 6-alpha-Hydroxy paclitaxel?
You can request a quote for 6-alpha-Hydroxy paclitaxel directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 6-alpha-Hydroxy paclitaxel?
Yes, CoreyChem provides custom synthesis services for 6-alpha-Hydroxy paclitaxel and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.