6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine
TL;DR: 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine (CAS 153436-73-8) is a chemical compound with molecular formula C15H9F3N4O2 and molecular weight 334.06775 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-nitro-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine
Also Known As: 6-nitro-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine, 6-NITRO-N-(3-(TRIFLUOROMETHYL)PHENYL)QUINAZOLIN-4-AMINE, 6-nitro-N-[3-(trifluoromethyl)phenyl]-4-quinazolinamine, N-[3-(Trifluoromethyl)phenyl]-6-nitroquinazolin-4-amine, 6-NITRO-N-(3-(TRIFLUOROMETHYL)PHENYL)-4-QUINAZOLINAMINE
Technical Specifications
| Molecular Formula | C15H9F3N4O2 |
| Molecular Weight | 334.06775 g/mol |
| XLogP | 4.1 |
| Topological Polar Surface Area (TPSA) | 83.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 334.06775 Da |
| Heavy Atoms | 24 |
| Complexity | 457.0 |
| SMILES | C1=CC(=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)[N+](=O)[O-])C(F)(F)F |
| InChIKey | FKOOZPWZRRDRTK-UHFFFAOYSA-N |
Chemical Property Profile of 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine
Property Insights of 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine
The XLogP value of 4.1 indicates that 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine. Following Lipinski's Rule of Five, 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine?
The CAS number of 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine is 153436-73-8.
What is the molecular formula of 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine?
The molecular formula of 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine is C15H9F3N4O2.
What is the molecular weight of 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine?
The molecular weight of 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine is 334.06775 g/mol.
Where can I buy 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine?
You can request a quote for 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine?
Yes, CoreyChem provides custom synthesis services for 6-Nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.