Fexofenadine Hydrochloride
TL;DR: Fexofenadine Hydrochloride (CAS 153439-40-8) is a chemical compound with molecular formula C32H40ClNO4 and molecular weight 537.2646 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid;hydrochloride
Also Known As: FEXOFENADINE HYDROCHLORIDE, FEXOFENADINE HCL, Allegra, Telfast, fexofenadine
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C32H40ClNO4 |
| Molecular Weight | 537.2646 g/mol |
| XLogP | 5.93 |
| Topological Polar Surface Area (TPSA) | 81.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 10 |
| Exact Mass | 537.2646 Da |
| Heavy Atoms | 38 |
| Complexity | 678.0 |
| Solubility | 71.8 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | CC(C)(C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O)C(=O)O.Cl |
| InChIKey | RRJFVPUCXDGFJB-UHFFFAOYSA-N |
Chemical Property Profile of Fexofenadine Hydrochloride
Property Insights of Fexofenadine Hydrochloride
The XLogP value of 5.93 indicates that Fexofenadine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Fexofenadine Hydrochloride. Following Lipinski's Rule of Five, Fexofenadine Hydrochloride has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Fexofenadine Hydrochloride?
The CAS number of Fexofenadine Hydrochloride is 153439-40-8.
What is the molecular formula of Fexofenadine Hydrochloride?
The molecular formula of Fexofenadine Hydrochloride is C32H40ClNO4.
What is the molecular weight of Fexofenadine Hydrochloride?
The molecular weight of Fexofenadine Hydrochloride is 537.2646 g/mol.
Where can I buy Fexofenadine Hydrochloride?
You can request a quote for Fexofenadine Hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Fexofenadine Hydrochloride?
Yes, CoreyChem provides custom synthesis services for Fexofenadine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.