NS 1619
TL;DR: NS 1619 (CAS 153587-01-0) is a chemical compound with molecular formula C15H8F6N2O2 and molecular weight 362.049 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one
3-[2-hydroxy-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-1H-benzimidazol-2-one
Also Known As: NS 1619, 1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one, NS 1619, powder, Lopac-N-170, Lopac0_000892
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H8F6N2O2 |
| Molecular Weight | 362.049 g/mol |
| XLogP | 3.7 |
| Topological Polar Surface Area (TPSA) | 52.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 1 |
| Exact Mass | 362.049 Da |
| Heavy Atoms | 25 |
| Complexity | 523.0 |
| SMILES | C1=CC2=C(C=C1C(F)(F)F)NC(=O)N2C3=C(C=CC(=C3)C(F)(F)F)O |
| InChIKey | YLFMCMWKHSDUCT-UHFFFAOYSA-N |
Product Description
Applications: NS 1619 is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies NS 1619 (CAS 153587-01-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, NS 1619 (CAS 153587-01-0) has the molecular formula C15H8F6N2O2 and a molecular weight of 362.05 g/mol. It is also known as NS-1619 and NS 1619.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of NS 1619
Property Insights of NS 1619
The XLogP value of 3.7 indicates that NS 1619 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.6 Ų, NS 1619 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, NS 1619 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of NS 1619?
The CAS number of NS 1619 is 153587-01-0.
What is the molecular formula of NS 1619?
The molecular formula of NS 1619 is C15H8F6N2O2.
What is the molecular weight of NS 1619?
The molecular weight of NS 1619 is 362.049 g/mol.
What are the applications of NS 1619?
NS 1619 is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies NS 1619 (CAS 153587-01-0) with custom synthesis...
Where can I buy NS 1619?
You can request a quote for NS 1619 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for NS 1619?
Yes, CoreyChem provides custom synthesis services for NS 1619 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.