RL 218
TL;DR: RL 218 (CAS 153901-56-5) is a chemical compound with molecular formula C22H23ClN6 and molecular weight 406.16727 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
8-chloro-1-methyl-5-(4-methylpiperazin-1-yl)-6-phenyl-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine
Also Known As: Rl 218, 8-chloro-1-methyl-5-(4-methylpiperazin-1-yl)-6-phenyl-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine, 6H-(1,2,4)Triazolo(4,3-a)(1,5)benzodiazepine, 8-chloro-1-methyl-5-(4-methyl-1-piperazinyl)-6-phenyl-, 8-chloro-1-methyl-5-(4-methylpiperazin-1-yl)-6-phenyl-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine, 5-(4-methylpiperazinyl)-8-chloro-6-phenyl-6H-(1,2,4)triazolo(4,3-a)(1,5)benzodiazepine
Technical Specifications
| Molecular Formula | C22H23ClN6 |
| Molecular Weight | 406.16727 g/mol |
| XLogP | 4.9 |
| Topological Polar Surface Area (TPSA) | 40.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 406.16727 Da |
| Heavy Atoms | 29 |
| Complexity | 600.0 |
| SMILES | CC1=NN=C2N1C3=C(C=C(C=C3)Cl)N(C(=C2)N4CCN(CC4)C)C5=CC=CC=C5 |
| InChIKey | IVTYOJOLKCTFCX-UHFFFAOYSA-N |
Chemical Property Profile of RL 218
Property Insights of RL 218
The XLogP value of 4.9 indicates that RL 218 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.4 Ų, RL 218 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RL 218 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of RL 218?
The CAS number of RL 218 is 153901-56-5.
What is the molecular formula of RL 218?
The molecular formula of RL 218 is C22H23ClN6.
What is the molecular weight of RL 218?
The molecular weight of RL 218 is 406.16727 g/mol.
Where can I buy RL 218?
You can request a quote for RL 218 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for RL 218?
Yes, CoreyChem provides custom synthesis services for RL 218 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.