3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide
TL;DR: 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide (CAS 153949-67-8) is a chemical compound with molecular formula C18H14ClFN2O3 and molecular weight 360.0677 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide
Also Known As: BAS 01923312, 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide, AB00110493-01, 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide, AN-829/40876264
Technical Specifications
| Molecular Formula | C18H14ClFN2O3 |
| Molecular Weight | 360.0677 g/mol |
| XLogP | 4.0 |
| Topological Polar Surface Area (TPSA) | 64.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 360.0677 Da |
| Heavy Atoms | 25 |
| Complexity | 462.0 |
| SMILES | CC1=C(C(=NO1)C2=C(C=CC=C2Cl)F)C(=O)NC3=CC=C(C=C3)OC |
| InChIKey | MLNQXHMNLQNTAS-UHFFFAOYSA-N |
Chemical Property Profile of 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide
Property Insights of 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide
The XLogP value of 4.0 indicates that 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide. Following Lipinski's Rule of Five, 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide?
The CAS number of 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide is 153949-67-8.
What is the molecular formula of 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide?
The molecular formula of 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide is C18H14ClFN2O3.
What is the molecular weight of 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide?
The molecular weight of 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide is 360.0677 g/mol.
Where can I buy 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide?
You can request a quote for 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide?
Yes, CoreyChem provides custom synthesis services for 3-(2-chloro-6-fluorophenyl)-N-(4-methoxyphenyl)-5-methyl-4-isoxazolecarboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.