3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one
TL;DR: 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one (CAS 154088-97-8) is a chemical compound with molecular formula C15H11FN2O and molecular weight 254.08554 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(4-fluorophenyl)-4-methylidene-1H-quinazolin-2-one
Also Known As: 3-(4-fluorophenyl)-4-methylidene-1H-quinazolin-2-one, 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one, 3-(4-fluorophenyl)-4-methylidene-3,4-dihydroquinazolin-2(1H)-one, 3-(4-fluorophenyl)-4-methylene-1,3-dihydroquinazolin-2-one, 3-(4-FLUOROPHENYL)-4-METHYLENE-3,4-DIHYDRO-2(1H)-QUINAZOLINONE
Technical Specifications
| Molecular Formula | C15H11FN2O |
| Molecular Weight | 254.08554 g/mol |
| XLogP | 3.0 |
| Topological Polar Surface Area (TPSA) | 32.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 254.08554 Da |
| Heavy Atoms | 19 |
| Complexity | 376.0 |
| SMILES | C=C1C2=CC=CC=C2NC(=O)N1C3=CC=C(C=C3)F |
| InChIKey | IMDCACOBNSQGQC-UHFFFAOYSA-N |
Chemical Property Profile of 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one
Property Insights of 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one
The XLogP value of 3.0 indicates that 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.3 Ų, 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one?
The CAS number of 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one is 154088-97-8.
What is the molecular formula of 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one?
The molecular formula of 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one is C15H11FN2O.
What is the molecular weight of 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one?
The molecular weight of 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one is 254.08554 g/mol.
Where can I buy 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one?
You can request a quote for 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one?
Yes, CoreyChem provides custom synthesis services for 3-(4-fluorophenyl)-4-methylene-3,4-dihydroquinazolin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.