6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one
TL;DR: 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one (CAS 154554-41-3) is a chemical compound with molecular formula C16H10FNO3 and molecular weight 283.06448 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-(2-fluorophenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one
Also Known As: CHM-1 hydrate, CHM 1, 154554-41-3 (anhydrous), Tox21_500741, EX-A11876
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H10FNO3 |
| Molecular Weight | 283.06448 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 47.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 283.06448 Da |
| Heavy Atoms | 21 |
| Complexity | 466.0 |
| SMILES | C1OC2=C(O1)C=C3C(=C2)C(=O)C=C(N3)C4=CC=CC=C4F |
| InChIKey | ZMYDAPJHGNEFGQ-UHFFFAOYSA-N |
Chemical Property Profile of 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one
Property Insights of 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one
The XLogP value of 3.1 indicates that 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.6 Ų, 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one?
The CAS number of 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one is 154554-41-3.
What is the molecular formula of 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one?
The molecular formula of 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one is C16H10FNO3.
What is the molecular weight of 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one?
The molecular weight of 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one is 283.06448 g/mol.
Where can I buy 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one?
You can request a quote for 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one?
Yes, CoreyChem provides custom synthesis services for 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.