2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one
TL;DR: 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one (CAS 1549-78-6) is a chemical compound with molecular formula C10H11F3N4O and molecular weight 260.0885 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,2,2-trifluoro-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Also Known As: 2-[4-(trifluoroacetyl)-1-piperazinyl]pyrimidine, 2,2,2-Trifluoro-1-(4-(pyrimidin-2-yl)piperazin-1-yl)ethan-1-one, 2,2,2-trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one, 2,2,2-trifluoro-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone, 2,2,2-trifluoro-1-[4-(pyrimidin-2-yl)piperazin-1-yl]ethanone
Technical Specifications
| Molecular Formula | C10H11F3N4O |
| Molecular Weight | 260.0885 g/mol |
| XLogP | 1.0 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 1 |
| Exact Mass | 260.0885 Da |
| Heavy Atoms | 18 |
| Complexity | 296.0 |
| SMILES | C1CN(CCN1C2=NC=CC=N2)C(=O)C(F)(F)F |
| InChIKey | WCMVNWLWFQNPTM-UHFFFAOYSA-N |
Chemical Property Profile of 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one
Property Insights of 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one. With a topological polar surface area (TPSA) of 49.3 Ų, 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one?
The CAS number of 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one is 1549-78-6.
What is the molecular formula of 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one?
The molecular formula of 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one is C10H11F3N4O.
What is the molecular weight of 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one?
The molecular weight of 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one is 260.0885 g/mol.
Where can I buy 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one?
You can request a quote for 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one?
Yes, CoreyChem provides custom synthesis services for 2,2,2-Trifluoro-1-(4-pyrimidin-2-ylpiperazinyl)ethan-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.