4'-Dehydroxy-4'-fluoroamodiaquine
TL;DR: 4'-Dehydroxy-4'-fluoroamodiaquine (CAS 155020-42-1) is a chemical compound with molecular formula C20H21ClFN3 and molecular weight 357.1408 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
7-chloro-N-[3-(diethylaminomethyl)-4-fluorophenyl]quinolin-4-amine
Also Known As: 4'-Dehydroxy-4'-fluoroamodiaquine, 4/'-Dehydroxy-4/'-fluoroamodiaquine, 4-Quinolinamine, 7-chloro-N-(3-((diethylamino)methyl)-4-fluorophenyl)-, 7-CHLORO-N-{3-[(DIETHYLAMINO)METHYL]-4-FLUOROPHENYL}QUINOLIN-4-AMINE, 7-chloro-N-[3-(diethylaminomethyl)-4-fluorophenyl]quinolin-4-amine
Technical Specifications
| Molecular Formula | C20H21ClFN3 |
| Molecular Weight | 357.1408 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 28.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 357.1408 Da |
| Heavy Atoms | 25 |
| Complexity | 406.0 |
| SMILES | CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)F |
| InChIKey | KMLKPUNXHVNTOM-UHFFFAOYSA-N |
Chemical Property Profile of 4'-Dehydroxy-4'-fluoroamodiaquine
Property Insights of 4'-Dehydroxy-4'-fluoroamodiaquine
The XLogP value of 3.1 indicates that 4'-Dehydroxy-4'-fluoroamodiaquine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.2 Ų, 4'-Dehydroxy-4'-fluoroamodiaquine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4'-Dehydroxy-4'-fluoroamodiaquine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4'-Dehydroxy-4'-fluoroamodiaquine?
The CAS number of 4'-Dehydroxy-4'-fluoroamodiaquine is 155020-42-1.
What is the molecular formula of 4'-Dehydroxy-4'-fluoroamodiaquine?
The molecular formula of 4'-Dehydroxy-4'-fluoroamodiaquine is C20H21ClFN3.
What is the molecular weight of 4'-Dehydroxy-4'-fluoroamodiaquine?
The molecular weight of 4'-Dehydroxy-4'-fluoroamodiaquine is 357.1408 g/mol.
Where can I buy 4'-Dehydroxy-4'-fluoroamodiaquine?
You can request a quote for 4'-Dehydroxy-4'-fluoroamodiaquine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4'-Dehydroxy-4'-fluoroamodiaquine?
Yes, CoreyChem provides custom synthesis services for 4'-Dehydroxy-4'-fluoroamodiaquine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.