TL;DR: 5'-methyl-3-(4-methylphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione (CAS 155425-88-0) is a chemical compound with molecular formula C18H16N2O2S and molecular weight 324.09326 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5'-methyl-3-(4-methylphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione
Also Known As: AP-407/40710841, 5'-methyl-3-(4-methylphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione, 10-methyl-3-(4-methylphenyl)spiro[1,3-thiazolidine-2,3'-indoline]-4,7-dione, 5-Methyl-3'-(4-methylphenyl)spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione, 5-Methyl-3a(2)-(4-methylphenyl)spiro[3H-indole-3,2a(2)-thiazolidine]-2,4a(2)(1H)-dione
| Molecular Formula | C18H16N2O2S |
| Molecular Weight | 324.09326 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 74.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 324.09326 Da |
| Heavy Atoms | 23 |
| Complexity | 517.0 |
| SMILES | CC1=CC=C(C=C1)N2C(=O)CSC23C4=C(C=CC(=C4)C)NC3=O |
| InChIKey | QVGMCDLRKDXWBB-UHFFFAOYSA-N |
The XLogP value of 3.1 indicates that 5'-methyl-3-(4-methylphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 74.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 5'-methyl-3-(4-methylphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione. Following Lipinski's Rule of Five, 5'-methyl-3-(4-methylphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of 5'-methyl-3-(4-methylphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione is 155425-88-0.
The molecular formula of 5'-methyl-3-(4-methylphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione is C18H16N2O2S.
The molecular weight of 5'-methyl-3-(4-methylphenyl)spiro[1,3-thiazolidine-2,3'-1H-indole]-2',4-dione is 324.09326 g/mol.
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