2,5-Difluorophenylacetyl chloride
TL;DR: 2,5-Difluorophenylacetyl chloride (CAS 157033-23-3) is a chemical compound with molecular formula C8H5ClF2O and molecular weight 189.9997 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(2,5-difluorophenyl)acetyl chloride
Also Known As: 2,5-Difluorophenylacetyl chloride, 2-(2,5-difluorophenyl)acetyl chloride, (2,5-difluoro-phenyl)-acetyl chloride, 2,5-difluorophenyl acetyl chloride, 2,5-Difluorophenylacetylchloride
Technical Specifications
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 189.9997 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 17.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 189.9997 Da |
| Heavy Atoms | 12 |
| Complexity | 174.0 |
| SMILES | C1=CC(=C(C=C1F)CC(=O)Cl)F |
| InChIKey | LQGHDMOEOHWRGX-UHFFFAOYSA-N |
Chemical Property Profile of 2,5-Difluorophenylacetyl chloride
Property Insights of 2,5-Difluorophenylacetyl chloride
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2,5-Difluorophenylacetyl chloride. With a topological polar surface area (TPSA) of 17.1 Ų, 2,5-Difluorophenylacetyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,5-Difluorophenylacetyl chloride has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2,5-Difluorophenylacetyl chloride?
The CAS number of 2,5-Difluorophenylacetyl chloride is 157033-23-3.
What is the molecular formula of 2,5-Difluorophenylacetyl chloride?
The molecular formula of 2,5-Difluorophenylacetyl chloride is C8H5ClF2O.
What is the molecular weight of 2,5-Difluorophenylacetyl chloride?
The molecular weight of 2,5-Difluorophenylacetyl chloride is 189.9997 g/mol.
Where can I buy 2,5-Difluorophenylacetyl chloride?
You can request a quote for 2,5-Difluorophenylacetyl chloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2,5-Difluorophenylacetyl chloride?
Yes, CoreyChem provides custom synthesis services for 2,5-Difluorophenylacetyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.