C49-Methyl rapamycin
TL;DR: C49-Methyl rapamycin (CAS 157054-84-7) is a chemical compound with molecular formula C52H81NO13 and molecular weight 927.5708 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-30-ethoxy-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Also Known As: C49-METHYL RAPAMYCIN, Rapamycin Impurity 10, Rapamycin C-7, analog 5b, RAD, (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-21-ethoxy-9,27-dihydroxy-3-((R)-1-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)propan-2-yl)-10-methoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentaone
Technical Specifications
| Molecular Formula | C52H81NO13 |
| Molecular Weight | 927.5708 g/mol |
| XLogP | 6.4 |
| Topological Polar Surface Area (TPSA) | 195.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 13 |
| Rotatable Bonds | 7 |
| Exact Mass | 927.5708 Da |
| Heavy Atoms | 66 |
| Complexity | 1770.0 |
| SMILES | CCO[C@H]\1C[C@@H]2CC[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H](CC(=O)[C@@H](/C=C(/[C@H]([C@H](C(=O)[C@@H](C[C@@H](/C=C/C=C/C=C1\C)C)C)OC)O)\C)C)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)O)C |
| InChIKey | GPZGXSFHPLUMHE-JQEUAWNDSA-N |
Chemical Property Profile of C49-Methyl rapamycin
Property Insights of C49-Methyl rapamycin
The XLogP value of 6.4 indicates that C49-Methyl rapamycin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 195.0 Ų indicates high polarity, suggesting C49-Methyl rapamycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, C49-Methyl rapamycin has 3 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of C49-Methyl rapamycin?
The CAS number of C49-Methyl rapamycin is 157054-84-7.
What is the molecular formula of C49-Methyl rapamycin?
The molecular formula of C49-Methyl rapamycin is C52H81NO13.
What is the molecular weight of C49-Methyl rapamycin?
The molecular weight of C49-Methyl rapamycin is 927.5708 g/mol.
Where can I buy C49-Methyl rapamycin?
You can request a quote for C49-Methyl rapamycin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for C49-Methyl rapamycin?
Yes, CoreyChem provides custom synthesis services for C49-Methyl rapamycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.