Trazodone Impurity 48
TL;DR: Trazodone Impurity 48 (CAS 157072-20-3) is a chemical compound with molecular formula C19H22ClN5O and molecular weight 371.15128 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[3-[4-(2-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Also Known As: Trazodone Impurity 48, Trazodone Impurity 58, 2-(3-(4-(2-chlorophenyl)piperazin-1-yl)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one, 8-[3-[4-(2-chlorophenyl)piperazin-1-yl]propyl]-1,7,8-triazabicyclo[4.3.0]nona-2,4,6-trien-9-one
Technical Specifications
| Molecular Formula | C19H22ClN5O |
| Molecular Weight | 371.15128 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 42.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 371.15128 Da |
| Heavy Atoms | 26 |
| Complexity | 611.0 |
| SMILES | C1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC=CC=C4Cl |
| InChIKey | WZFUPXDNTAVTTF-UHFFFAOYSA-N |
Chemical Property Profile of Trazodone Impurity 48
Property Insights of Trazodone Impurity 48
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trazodone Impurity 48. With a topological polar surface area (TPSA) of 42.4 Ų, Trazodone Impurity 48 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trazodone Impurity 48 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trazodone Impurity 48?
The CAS number of Trazodone Impurity 48 is 157072-20-3.
What is the molecular formula of Trazodone Impurity 48?
The molecular formula of Trazodone Impurity 48 is C19H22ClN5O.
What is the molecular weight of Trazodone Impurity 48?
The molecular weight of Trazodone Impurity 48 is 371.15128 g/mol.
Where can I buy Trazodone Impurity 48?
You can request a quote for Trazodone Impurity 48 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trazodone Impurity 48?
Yes, CoreyChem provides custom synthesis services for Trazodone Impurity 48 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.