Sirolimus Impurity 2
TL;DR: Sirolimus Impurity 2 (CAS 157182-37-1) is a chemical compound with molecular formula C51H79NO13 and molecular weight 913.5551 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30R,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Also Known As: rapamycin, Rapammune, Rapamune, Sirolimus, Cypher
Technical Specifications
| Molecular Formula | C51H79NO13 |
| Molecular Weight | 913.5551 g/mol |
| XLogP | 6.0 |
| Topological Polar Surface Area (TPSA) | 195.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 13 |
| Rotatable Bonds | 6 |
| Exact Mass | 913.5551 Da |
| Heavy Atoms | 65 |
| Complexity | 1760.0 |
| SMILES | C[C@@H]1CC[C@H]2C[C@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC |
| InChIKey | QFJCIRLUMZQUOT-RIPNRHRMSA-N |
Chemical Property Profile of Sirolimus Impurity 2
Property Insights of Sirolimus Impurity 2
The XLogP value of 6.0 indicates that Sirolimus Impurity 2 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 195.0 Ų indicates high polarity, suggesting Sirolimus Impurity 2 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Sirolimus Impurity 2 has 3 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Sirolimus Impurity 2?
The CAS number of Sirolimus Impurity 2 is 157182-37-1.
What is the molecular formula of Sirolimus Impurity 2?
The molecular formula of Sirolimus Impurity 2 is C51H79NO13.
What is the molecular weight of Sirolimus Impurity 2?
The molecular weight of Sirolimus Impurity 2 is 913.5551 g/mol.
Where can I buy Sirolimus Impurity 2?
You can request a quote for Sirolimus Impurity 2 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Sirolimus Impurity 2?
Yes, CoreyChem provides custom synthesis services for Sirolimus Impurity 2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.