R-84760 free base
TL;DR: R-84760 free base (CAS 157824-29-8) is a chemical compound with molecular formula C19H24Cl2N2OS and molecular weight 398.09863 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[(1S)-5,6-dichloro-2,3-dihydro-1H-inden-1-yl]-[(3R)-3-(pyrrolidin-1-ylmethyl)thiomorpholin-4-yl]methanone
Also Known As: R-84760 free base, R-84760, Thiomorpholine, 4-((5,6-dichloro-2,3-dihydro-1H-inden-1-yl)carbonyl)-3-(1-pyrrolidinylmethyl)-, (R-(R*,S*))-, (3R)-3-(1-pyrrolidinylmethyl)-4-[(1S)-5,6-dichloro-1-indanecarbonyl)thiomorpholine, (3R)-3-(Pyrrolizinomethyl)-4-[[(S)-5,6-dichloro-1-indanyl]carbonyl]tetrahydro-2H-1,4-thiazine
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H24Cl2N2OS |
| Molecular Weight | 398.09863 g/mol |
| XLogP | 4.0 |
| Topological Polar Surface Area (TPSA) | 48.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 398.09863 Da |
| Heavy Atoms | 25 |
| Complexity | 488.0 |
| SMILES | C1CCN(C1)C[C@@H]2CSCCN2C(=O)[C@H]3CCC4=CC(=C(C=C34)Cl)Cl |
| InChIKey | RJMVKKVRRJUURW-CABCVRRESA-N |
Chemical Property Profile of R-84760 free base
Property Insights of R-84760 free base
The XLogP value of 4.0 indicates that R-84760 free base is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.9 Ų, R-84760 free base exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, R-84760 free base has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of R-84760 free base?
The CAS number of R-84760 free base is 157824-29-8.
What is the molecular formula of R-84760 free base?
The molecular formula of R-84760 free base is C19H24Cl2N2OS.
What is the molecular weight of R-84760 free base?
The molecular weight of R-84760 free base is 398.09863 g/mol.
Where can I buy R-84760 free base?
You can request a quote for R-84760 free base directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for R-84760 free base?
Yes, CoreyChem provides custom synthesis services for R-84760 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.