6-(Trifluoromethyl)nicotinamide
TL;DR: 6-(Trifluoromethyl)nicotinamide (CAS 158062-71-6) is a chemical compound with molecular formula C7H5F3N2O and molecular weight 190.0354 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-(trifluoromethyl)pyridine-3-carboxamide
Also Known As: 6-(trifluoromethyl)nicotinamide, 6-(trifluoromethyl)pyridine-3-carboxamide, null, 6-Trifluoromethylnicotinamide, trifluoromethylnicotinamide
Technical Specifications
| Molecular Formula | C7H5F3N2O |
| Molecular Weight | 190.0354 g/mol |
| XLogP | 0.6 |
| Topological Polar Surface Area (TPSA) | 56.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 190.0354 Da |
| Heavy Atoms | 13 |
| Complexity | 204.0 |
| SMILES | C1=CC(=NC=C1C(=O)N)C(F)(F)F |
| InChIKey | RIKJKWNZUSPCCM-UHFFFAOYSA-N |
Chemical Property Profile of 6-(Trifluoromethyl)nicotinamide
Property Insights of 6-(Trifluoromethyl)nicotinamide
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-(Trifluoromethyl)nicotinamide. With a topological polar surface area (TPSA) of 56.0 Ų, 6-(Trifluoromethyl)nicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(Trifluoromethyl)nicotinamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 6-(Trifluoromethyl)nicotinamide?
The CAS number of 6-(Trifluoromethyl)nicotinamide is 158062-71-6.
What is the molecular formula of 6-(Trifluoromethyl)nicotinamide?
The molecular formula of 6-(Trifluoromethyl)nicotinamide is C7H5F3N2O.
What is the molecular weight of 6-(Trifluoromethyl)nicotinamide?
The molecular weight of 6-(Trifluoromethyl)nicotinamide is 190.0354 g/mol.
Where can I buy 6-(Trifluoromethyl)nicotinamide?
You can request a quote for 6-(Trifluoromethyl)nicotinamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 6-(Trifluoromethyl)nicotinamide?
Yes, CoreyChem provides custom synthesis services for 6-(Trifluoromethyl)nicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.