Rosuvastatin Impurity 77
TL;DR: Rosuvastatin Impurity 77 (CAS 1584149-34-7) is a chemical compound with molecular formula C22H28FN3O6S and molecular weight 481.16827 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(E,3S,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Also Known As: Rosuvastatin Impurity 77, Rosuvastatin Impurity 80, (3S,5S)-Rosuvastatin Calcium, Rosuvastatin EP Impurity B (SS-Isomer), ROSUVASTATIN (3S,5S)-ISOMER IMPURITY
Technical Specifications
| Molecular Formula | C22H28FN3O6S |
| Molecular Weight | 481.16827 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 149.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 10 |
| Exact Mass | 481.16827 Da |
| Heavy Atoms | 33 |
| Complexity | 767.0 |
| SMILES | CC(C)C1=NC(=NC(=C1/C=C/[C@H](C[C@@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C |
| InChIKey | BPRHUIZQVSMCRT-ZUQFGZKASA-N |
Chemical Property Profile of Rosuvastatin Impurity 77
Property Insights of Rosuvastatin Impurity 77
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Rosuvastatin Impurity 77. The TPSA of 149.0 Ų indicates high polarity, suggesting Rosuvastatin Impurity 77 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Rosuvastatin Impurity 77 has 3 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Rosuvastatin Impurity 77?
The CAS number of Rosuvastatin Impurity 77 is 1584149-34-7.
What is the molecular formula of Rosuvastatin Impurity 77?
The molecular formula of Rosuvastatin Impurity 77 is C22H28FN3O6S.
What is the molecular weight of Rosuvastatin Impurity 77?
The molecular weight of Rosuvastatin Impurity 77 is 481.16827 g/mol.
Where can I buy Rosuvastatin Impurity 77?
You can request a quote for Rosuvastatin Impurity 77 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Rosuvastatin Impurity 77?
Yes, CoreyChem provides custom synthesis services for Rosuvastatin Impurity 77 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.