1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid
TL;DR: 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid (CAS 158883-64-8) is a chemical compound with molecular formula C17H12F2N2O2 and molecular weight 314.08667 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(2,4-difluorophenyl)-3-(4-methylphenyl)pyrazole-5-carboxylic acid
Also Known As: 1-(2,4-difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid, SALOR-INT L323209-1EA, 1-(1-Amino-1H-pyrrol-2-yl)-ethanone, 1-(2,4-difluorophenyl)-3-(4-methylphenyl)-1H-pyrazole-5-carboxylic acid, 1-(2,4-Difluorophenyl)-3-(p-tolyl)-1H-pyrazole-5-carboxylic acid
Technical Specifications
| Molecular Formula | C17H12F2N2O2 |
| Molecular Weight | 314.08667 g/mol |
| XLogP | 4.0 |
| Topological Polar Surface Area (TPSA) | 55.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 314.08667 Da |
| Heavy Atoms | 23 |
| Complexity | 429.0 |
| SMILES | CC1=CC=C(C=C1)C2=NN(C(=C2)C(=O)O)C3=C(C=C(C=C3)F)F |
| InChIKey | HOLVOWXBVUHQLZ-UHFFFAOYSA-N |
Chemical Property Profile of 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid
Property Insights of 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid
The XLogP value of 4.0 indicates that 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.1 Ų, 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid?
The CAS number of 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid is 158883-64-8.
What is the molecular formula of 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid?
The molecular formula of 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid is C17H12F2N2O2.
What is the molecular weight of 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid?
The molecular weight of 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid is 314.08667 g/mol.
Where can I buy 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid?
You can request a quote for 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid?
Yes, CoreyChem provides custom synthesis services for 1-(2,4-Difluorophenyl)-3-p-tolyl-1h-pyrazole-5-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.