Everolimus
TL;DR: Everolimus (CAS 159351-69-6) is a chemical compound with molecular formula C53H83NO14 and molecular weight 957.58136 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(1R,9S,12S,15R,18R,19R,21R,23S,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Also Known As: Everolimus, Afinitor, Certican, Zortress, Votubia
Technical Specifications
| Molecular Formula | C53H83NO14 |
| Molecular Weight | 957.58136 g/mol |
| XLogP | 5.9 |
| Topological Polar Surface Area (TPSA) | 205.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 9 |
| Exact Mass | 957.58136 Da |
| Heavy Atoms | 68 |
| Complexity | 1810.0 |
| SMILES | C[C@@H]1CC[C@H]2C[C@@H](C(=CC=CC=C[C@H](C[C@H](C(=O)[C@@H]([C@@H](C(=C[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)C)O)OC)C)C)C)OC |
| InChIKey | HKVAMNSJSFKALM-DHGBBOBXSA-N |
Chemical Property Profile of Everolimus
Property Insights of Everolimus
The XLogP value of 5.9 indicates that Everolimus is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 205.0 Ų indicates high polarity, suggesting Everolimus may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Everolimus has 3 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Everolimus?
The CAS number of Everolimus is 159351-69-6.
What is the molecular formula of Everolimus?
The molecular formula of Everolimus is C53H83NO14.
What is the molecular weight of Everolimus?
The molecular weight of Everolimus is 957.58136 g/mol.
Where can I buy Everolimus?
You can request a quote for Everolimus directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Everolimus?
Yes, CoreyChem provides custom synthesis services for Everolimus and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.