1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-
TL;DR: 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)- (CAS 159872-59-0) is a chemical compound with molecular formula C21H28N6O3 and molecular weight 412.2223 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-[3-[4-(2,6-diaminopyrimidin-4-yl)piperazin-1-yl]-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one
Also Known As: 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-, 6-[3-[4-(2,6-diaminopyrimidin-4-yl)piperazin-1-yl]-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one, 6-{3-[4-(6-Amino-2-imino-1,2-dihydropyrimidin-4-yl)piperazin-1-yl]-2-hydroxypropoxy}-3,4-dihydronaphthalen-1(2H)-one
Technical Specifications
| Molecular Formula | C21H28N6O3 |
| Molecular Weight | 412.2223 g/mol |
| XLogP | 0.9 |
| Topological Polar Surface Area (TPSA) | 131.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 6 |
| Exact Mass | 412.2223 Da |
| Heavy Atoms | 30 |
| Complexity | 573.0 |
| SMILES | C1CC2=C(C=CC(=C2)OCC(CN3CCN(CC3)C4=NC(=NC(=C4)N)N)O)C(=O)C1 |
| InChIKey | HDWFOMNKLWVZCU-UHFFFAOYSA-N |
Chemical Property Profile of 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-
Property Insights of 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-
The XLogP value of 0.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-. The TPSA of 131.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-. Following Lipinski's Rule of Five, 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)- has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-?
The CAS number of 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)- is 159872-59-0.
What is the molecular formula of 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-?
The molecular formula of 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)- is C21H28N6O3.
What is the molecular weight of 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-?
The molecular weight of 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)- is 412.2223 g/mol.
Where can I buy 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-?
You can request a quote for 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)- directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)-?
Yes, CoreyChem provides custom synthesis services for 1(2H)-Naphthalenone, 3,4-dihydro-6-(3-(4-(2,6-diamino-4-pyrimidinyl)-1-piperazinyl)-2-hydroxypropoxy)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.