8-(Trifluoromethyl)quinolin-5-amine
TL;DR: 8-(Trifluoromethyl)quinolin-5-amine (CAS 161431-57-8) is a chemical compound with molecular formula C10H7F3N2 and molecular weight 212.05614 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
8-(trifluoromethyl)quinolin-5-amine
Also Known As: 8-(trifluoromethyl)quinolin-5-amine, 5-Quinolinamine, 8-(trifluoromethyl)-, 5-Amino-8-(trifluoromethyl)quinoline, 8-(trifluoromethyl)-5-quinolinamine, 8-Trifluoromethyl-quinolin-5-ylamine
Technical Specifications
| Molecular Formula | C10H7F3N2 |
| Molecular Weight | 212.05614 g/mol |
| XLogP | 1.8 |
| Topological Polar Surface Area (TPSA) | 38.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 0 |
| Exact Mass | 212.05614 Da |
| Heavy Atoms | 15 |
| Complexity | 229.0 |
| SMILES | C1=CC2=C(C=CC(=C2N=C1)C(F)(F)F)N |
| InChIKey | MFLUPLVEVVDFOD-UHFFFAOYSA-N |
Chemical Property Profile of 8-(Trifluoromethyl)quinolin-5-amine
Property Insights of 8-(Trifluoromethyl)quinolin-5-amine
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-(Trifluoromethyl)quinolin-5-amine. With a topological polar surface area (TPSA) of 38.9 Ų, 8-(Trifluoromethyl)quinolin-5-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-(Trifluoromethyl)quinolin-5-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 8-(Trifluoromethyl)quinolin-5-amine?
The CAS number of 8-(Trifluoromethyl)quinolin-5-amine is 161431-57-8.
What is the molecular formula of 8-(Trifluoromethyl)quinolin-5-amine?
The molecular formula of 8-(Trifluoromethyl)quinolin-5-amine is C10H7F3N2.
What is the molecular weight of 8-(Trifluoromethyl)quinolin-5-amine?
The molecular weight of 8-(Trifluoromethyl)quinolin-5-amine is 212.05614 g/mol.
Where can I buy 8-(Trifluoromethyl)quinolin-5-amine?
You can request a quote for 8-(Trifluoromethyl)quinolin-5-amine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 8-(Trifluoromethyl)quinolin-5-amine?
Yes, CoreyChem provides custom synthesis services for 8-(Trifluoromethyl)quinolin-5-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.