RWJ 50271
TL;DR: RWJ 50271 (CAS 162112-37-0) is a chemical compound with molecular formula C18H17F3N4O2S and molecular weight 410.10242 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(3-hydroxypropyl)-5-methyl-1-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]pyrazole-4-carboxamide
Also Known As: RWJ 50271, EX-A5356, N-(3-hydroxypropyl)-5-methyl-1-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]pyrazole-4-carboxamide, N-(3-Hydroxypropyl)-5-methyl-1-(4-(3-(trifluoromethyl)phenyl)thiazol-2-yl)-1H-pyrazole-4-carboxamide, N-(3-Hydroxypropyl)-5-methyl-1-[-4-[3-(trifluoromethyl)phenyl)]-2-thiazolyl]-1H-pyrazole-4-carboxamide
Technical Specifications
| Molecular Formula | C18H17F3N4O2S |
| Molecular Weight | 410.10242 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 108.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Exact Mass | 410.10242 Da |
| Heavy Atoms | 28 |
| Complexity | 539.0 |
| SMILES | CC1=C(C=NN1C2=NC(=CS2)C3=CC(=CC=C3)C(F)(F)F)C(=O)NCCCO |
| InChIKey | HOFGTYCLOKDAES-UHFFFAOYSA-N |
Chemical Property Profile of RWJ 50271
Property Insights of RWJ 50271
The XLogP value of 3.2 indicates that RWJ 50271 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 108.0 Ų falls within the moderate polarity range, balancing permeability and solubility for RWJ 50271. Following Lipinski's Rule of Five, RWJ 50271 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of RWJ 50271?
The CAS number of RWJ 50271 is 162112-37-0.
What is the molecular formula of RWJ 50271?
The molecular formula of RWJ 50271 is C18H17F3N4O2S.
What is the molecular weight of RWJ 50271?
The molecular weight of RWJ 50271 is 410.10242 g/mol.
Where can I buy RWJ 50271?
You can request a quote for RWJ 50271 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for RWJ 50271?
Yes, CoreyChem provides custom synthesis services for RWJ 50271 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.