6alpha-Methylhydrocortisone
TL;DR: 6alpha-Methylhydrocortisone (CAS 1625-39-4) is a chemical compound with molecular formula C22H32O5 and molecular weight 376.22498 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: 6a-Methyl Hydrocortisone, A-Methylcortisol, PREMEDROL, 6alpha-methylcortisol, 6alpha-methylhydrocortisone
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H32O5 |
| Molecular Weight | 376.22498 g/mol |
| XLogP | 1.9 |
| Topological Polar Surface Area (TPSA) | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 376.22498 Da |
| Heavy Atoms | 27 |
| Complexity | 713.0 |
| SMILES | C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)CC4)C)O)C)(C(=O)CO)O |
| InChIKey | FQWLSWNUHFREIQ-PJHHCJLFSA-N |
Chemical Property Profile of 6alpha-Methylhydrocortisone
Property Insights of 6alpha-Methylhydrocortisone
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6alpha-Methylhydrocortisone. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 6alpha-Methylhydrocortisone. Following Lipinski's Rule of Five, 6alpha-Methylhydrocortisone has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 6alpha-Methylhydrocortisone?
The CAS number of 6alpha-Methylhydrocortisone is 1625-39-4.
What is the molecular formula of 6alpha-Methylhydrocortisone?
The molecular formula of 6alpha-Methylhydrocortisone is C22H32O5.
What is the molecular weight of 6alpha-Methylhydrocortisone?
The molecular weight of 6alpha-Methylhydrocortisone is 376.22498 g/mol.
Where can I buy 6alpha-Methylhydrocortisone?
You can request a quote for 6alpha-Methylhydrocortisone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 6alpha-Methylhydrocortisone?
Yes, CoreyChem provides custom synthesis services for 6alpha-Methylhydrocortisone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.