TL;DR: (2R,4R)-4-hydroxypiperidine-2-carboxylic acid (CAS 16275-25-5) is a chemical compound with molecular formula C6H11NO3 and molecular weight 145.0739 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R,4R)-4-hydroxypiperidine-2-carboxylic acid
Also Known As: Pegaline, argon,hexahydrate, (2R,4R)-4-hydroxypiperidine-2-carboxylic acid, 4-Hydroxypipecolic acid, trans-4-hydroxypipecolic acid
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
| Molecular Formula | C6H11NO3 |
| Molecular Weight | 145.0739 g/mol |
| XLogP | -3.0 |
| Topological Polar Surface Area (TPSA) | 69.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 145.0739 Da |
| Heavy Atoms | 10 |
| Complexity | 137.0 |
| SMILES | C1CN[C@H](C[C@@H]1O)C(=O)O |
| InChIKey | KRHNXNZBLHHEIU-RFZPGFLSSA-N |
The XLogP value of -3.0 indicates that (2R,4R)-4-hydroxypiperidine-2-carboxylic acid is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 69.6 Ų falls within the moderate polarity range, balancing permeability and solubility for (2R,4R)-4-hydroxypiperidine-2-carboxylic acid. Following Lipinski's Rule of Five, (2R,4R)-4-hydroxypiperidine-2-carboxylic acid has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of (2R,4R)-4-hydroxypiperidine-2-carboxylic acid is 16275-25-5.
The molecular formula of (2R,4R)-4-hydroxypiperidine-2-carboxylic acid is C6H11NO3.
The molecular weight of (2R,4R)-4-hydroxypiperidine-2-carboxylic acid is 145.0739 g/mol.
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