Ezetimibe
TL;DR: Ezetimibe (CAS 163222-33-1) is a chemical compound with molecular formula C24H21F2NO3 and molecular weight 409.14896 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3R,4S)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Also Known As: Ezetimibe, Spectrum2_000489, Spectrum3_001005, Spectrum4_001133, Spectrum5_001552
Technical Specifications
| Molecular Formula | C24H21F2NO3 |
| Molecular Weight | 409.14896 g/mol |
| XLogP | 4.0 |
| Topological Polar Surface Area (TPSA) | 60.8 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 409.14896 Da |
| Heavy Atoms | 30 |
| Complexity | 567.0 |
| SMILES | C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O |
| InChIKey | OLNTVTPDXPETLC-OJVMETQDSA-N |
Chemical Property Profile of Ezetimibe
Property Insights of Ezetimibe
The XLogP value of 4.0 indicates that Ezetimibe is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Ezetimibe. Following Lipinski's Rule of Five, Ezetimibe has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Ezetimibe?
The CAS number of Ezetimibe is 163222-33-1.
What is the molecular formula of Ezetimibe?
The molecular formula of Ezetimibe is C24H21F2NO3.
What is the molecular weight of Ezetimibe?
The molecular weight of Ezetimibe is 409.14896 g/mol.
Where can I buy Ezetimibe?
You can request a quote for Ezetimibe directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Ezetimibe?
Yes, CoreyChem provides custom synthesis services for Ezetimibe and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.