TAPI1
TL;DR: TAPI1 (CAS 163847-77-6) is a chemical compound with molecular formula C26H37N5O5 and molecular weight 499.27948 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[(2S)-1-[[(2S)-1-(2-aminoethylamino)-1-oxopropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide
Also Known As: TAPI1, InSolution™ TAPI-1, (S,S)-TAPI-1, TAPI 1, TNF-alpha Protease Inhibitor-1
Technical Specifications
| Molecular Formula | C26H37N5O5 |
| Molecular Weight | 499.27948 g/mol |
| XLogP | 1.3 |
| Topological Polar Surface Area (TPSA) | 163.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 13 |
| Exact Mass | 499.27948 Da |
| Heavy Atoms | 36 |
| Complexity | 746.0 |
| SMILES | C[C@@H](C(=O)NCCN)NC(=O)[C@H](CC1=CC2=CC=CC=C2C=C1)NC(=O)C(CC(C)C)CC(=O)NO |
| InChIKey | AWNBSWDIOCXWJW-OWHMDLSXSA-N |
Chemical Property Profile of TAPI1
Property Insights of TAPI1
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for TAPI1. The TPSA of 163.0 Ų indicates high polarity, suggesting TAPI1 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, TAPI1 has 6 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of TAPI1?
The CAS number of TAPI1 is 163847-77-6.
What is the molecular formula of TAPI1?
The molecular formula of TAPI1 is C26H37N5O5.
What is the molecular weight of TAPI1?
The molecular weight of TAPI1 is 499.27948 g/mol.
Where can I buy TAPI1?
You can request a quote for TAPI1 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for TAPI1?
Yes, CoreyChem provides custom synthesis services for TAPI1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.