Dutasteride
TL;DR: Dutasteride (CAS 1646570-98-0) is a chemical compound with molecular formula C27H30F6N2O2 and molecular weight 528.2211 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
Also Known As: Dutasteride, Avodart, Avolve, Duastride, Duagen
Technical Specifications
| Molecular Formula | C27H30F6N2O2 |
| Molecular Weight | 528.2211 g/mol |
| XLogP | 5.4 |
| Topological Polar Surface Area (TPSA) | 58.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 528.2211 Da |
| Heavy Atoms | 37 |
| Complexity | 964.0 |
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CC[C@@H]5[C@@]3(C=CC(=O)N5)C |
| InChIKey | JWJOTENAMICLJG-QWBYCMEYSA-N |
Chemical Property Profile of Dutasteride
Property Insights of Dutasteride
The XLogP value of 5.4 indicates that Dutasteride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.2 Ų, Dutasteride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dutasteride has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Dutasteride?
The CAS number of Dutasteride is 1646570-98-0.
What is the molecular formula of Dutasteride?
The molecular formula of Dutasteride is C27H30F6N2O2.
What is the molecular weight of Dutasteride?
The molecular weight of Dutasteride is 528.2211 g/mol.
Where can I buy Dutasteride?
You can request a quote for Dutasteride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dutasteride?
Yes, CoreyChem provides custom synthesis services for Dutasteride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.