5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine
TL;DR: 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine (CAS 164848-20-8) is a chemical compound with molecular formula C10H13ClN2O5 and molecular weight 276.0513 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(2R,4R,5S)-4,5-bis(hydroxymethyl)oxolan-2-yl]-5-chloropyrimidine-2,4-dione
Also Known As: 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine, 3 -(Hydroxymethyl)-2 ,3 -dideoxy-5-chlorouridine, 1-[(2S,4R,5R)-4,5-bis(hydroxymethyl)oxolan-2-yl]-5-chloro-pyrimidine-2,4-dione, 1-[(2R,4R,5S)-4,5-bis(hydroxymethyl)oxolan-2-yl]-5-chloro-1,2,3,4-tetrahydropyrimidine-2,4-dione
Technical Specifications
| Molecular Formula | C10H13ClN2O5 |
| Molecular Weight | 276.0513 g/mol |
| XLogP | -0.9 |
| Topological Polar Surface Area (TPSA) | 99.1 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 276.0513 Da |
| Heavy Atoms | 18 |
| Complexity | 400.0 |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)Cl)CO)CO |
| InChIKey | POSIPYYJCLYVQB-LPBLVHEISA-N |
Chemical Property Profile of 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine
Property Insights of 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine
The XLogP value of -0.9 indicates that 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 99.1 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine. Following Lipinski's Rule of Five, 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine?
The CAS number of 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine is 164848-20-8.
What is the molecular formula of 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine?
The molecular formula of 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine is C10H13ClN2O5.
What is the molecular weight of 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine?
The molecular weight of 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine is 276.0513 g/mol.
Where can I buy 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine?
You can request a quote for 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine?
Yes, CoreyChem provides custom synthesis services for 5-Chloro-2',3'-dideoxy-3'-(hydroxymethyl)uridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.