CB 184
TL;DR: CB 184 (CAS 165307-47-1) is a chemical compound with molecular formula C22H21Cl2NO2 and molecular weight 401.09494 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(1R,5R,8E)-8-[(3,4-dichlorophenyl)methylidene]-5-(3-hydroxyphenyl)-2-methyl-2-azabicyclo[3.3.1]nonan-7-one
Also Known As: CB 184, 3-Ethoxy-androsta-3,5-dien-17-ol-d3, NCI60_028024, (1R,5R,8E)-8-[(3,4-dichlorophenyl)methylidene]-5-(3-hydroxyphenyl)-2-methyl-2-azabicyclo[3.3.1]nonan-7-one, (1R,5R,8E)-5-(3-Hydroxyphenyl)-8-(3,4-dichlorobenzylidene)-2-methyl-2-azabicyclo[3.3.1]nonan-7-one
Technical Specifications
| Molecular Formula | C22H21Cl2NO2 |
| Molecular Weight | 401.09494 g/mol |
| XLogP | 4.9 |
| Topological Polar Surface Area (TPSA) | 40.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 401.09494 Da |
| Heavy Atoms | 27 |
| Complexity | 609.0 |
| SMILES | CN1CC[C@]2(C[C@@H]1/C(=C\C3=CC(=C(C=C3)Cl)Cl)/C(=O)C2)C4=CC(=CC=C4)O |
| InChIKey | SSPWSCFMVXPMNL-COSXAGSESA-N |
Chemical Property Profile of CB 184
Property Insights of CB 184
The XLogP value of 4.9 indicates that CB 184 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.5 Ų, CB 184 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, CB 184 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of CB 184?
The CAS number of CB 184 is 165307-47-1.
What is the molecular formula of CB 184?
The molecular formula of CB 184 is C22H21Cl2NO2.
What is the molecular weight of CB 184?
The molecular weight of CB 184 is 401.09494 g/mol.
Where can I buy CB 184?
You can request a quote for CB 184 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for CB 184?
Yes, CoreyChem provides custom synthesis services for CB 184 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.