Lamivudine; zidovudine
TL;DR: Lamivudine; zidovudine (CAS 165456-81-5) is a chemical compound with molecular formula C18H24N8O7S and molecular weight 496.14886 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one;1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: Combivir, Lamivudine and zidovudine, Combivir(TM), Lamivudine/Zidovudine, Zidovudine / lamivudine
Technical Specifications
| Molecular Formula | C18H24N8O7S |
| Molecular Weight | 496.14886 g/mol |
| XLogP | -0.79038 |
| Topological Polar Surface Area (TPSA) | 207.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 5 |
| Exact Mass | 496.14886 Da |
| Heavy Atoms | 34 |
| Complexity | 815.0 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-].C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N |
| InChIKey | LHCOVOKZWQYODM-CPEOKENHSA-N |
Chemical Property Profile of Lamivudine; zidovudine
Property Insights of Lamivudine; zidovudine
The XLogP value of -0.79038 indicates that Lamivudine; zidovudine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 207.0 Ų indicates high polarity, suggesting Lamivudine; zidovudine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Lamivudine; zidovudine has 4 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Lamivudine; zidovudine?
The CAS number of Lamivudine; zidovudine is 165456-81-5.
What is the molecular formula of Lamivudine; zidovudine?
The molecular formula of Lamivudine; zidovudine is C18H24N8O7S.
What is the molecular weight of Lamivudine; zidovudine?
The molecular weight of Lamivudine; zidovudine is 496.14886 g/mol.
Where can I buy Lamivudine; zidovudine?
You can request a quote for Lamivudine; zidovudine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Lamivudine; zidovudine?
Yes, CoreyChem provides custom synthesis services for Lamivudine; zidovudine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.