Vofopitant
TL;DR: Vofopitant (CAS 168266-90-8) is a chemical compound with molecular formula C21H23F3N6O and molecular weight 432.18854 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methyl]-2-phenylpiperidin-3-amine
Also Known As: Vofopitant, Vofopitant [INN], GR 205171, GR 226206, L-796,325
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H23F3N6O |
| Molecular Weight | 432.18854 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 76.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 6 |
| Exact Mass | 432.18854 Da |
| Heavy Atoms | 31 |
| Complexity | 562.0 |
| SMILES | COC1=C(C=C(C=C1)N2C(=NN=N2)C(F)(F)F)CNC3CCCNC3C4=CC=CC=C4 |
| InChIKey | XILNRORTJVDYRH-UHFFFAOYSA-N |
Chemical Property Profile of Vofopitant
Property Insights of Vofopitant
The XLogP value of 3.1 indicates that Vofopitant is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Vofopitant. Following Lipinski's Rule of Five, Vofopitant has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Vofopitant?
The CAS number of Vofopitant is 168266-90-8.
What is the molecular formula of Vofopitant?
The molecular formula of Vofopitant is C21H23F3N6O.
What is the molecular weight of Vofopitant?
The molecular weight of Vofopitant is 432.18854 g/mol.
Where can I buy Vofopitant?
You can request a quote for Vofopitant directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Vofopitant?
Yes, CoreyChem provides custom synthesis services for Vofopitant and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.