Tadalafil
TL;DR: Tadalafil (CAS 171596-29-5) is a chemical compound with molecular formula C22H19N3O4 and molecular weight 389.13754 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R,8R)-2-(1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
Also Known As: Tadalafil, Cialis, Tadanafil, ADCIRCA, Tadalafilo
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H19N3O4 |
| Molecular Weight | 389.13754 g/mol |
| XLogP | 2.3 |
| Topological Polar Surface Area (TPSA) | 74.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 389.13754 Da |
| Heavy Atoms | 29 |
| Complexity | 702.0 |
| Melting Point | 301-302 °C |
| Vapor Pressure | 2.2X10-14 mm Hg at 25 °C /Estimated/ |
| Solubility | Practically insoluble in water |
| SMILES | CN1CC(=O)N2[C@@H](C1=O)CC3=C([C@H]2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36 |
| InChIKey | WOXKDUGGOYFFRN-IIBYNOLFSA-N |
Chemical Property Profile of Tadalafil
Property Insights of Tadalafil
The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tadalafil. The TPSA of 74.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Tadalafil. Following Lipinski's Rule of Five, Tadalafil has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tadalafil?
The CAS number of Tadalafil is 171596-29-5.
What is the molecular formula of Tadalafil?
The molecular formula of Tadalafil is C22H19N3O4.
What is the molecular weight of Tadalafil?
The molecular weight of Tadalafil is 389.13754 g/mol.
Where can I buy Tadalafil?
You can request a quote for Tadalafil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tadalafil?
Yes, CoreyChem provides custom synthesis services for Tadalafil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.