Riluzole
TL;DR: Riluzole (CAS 1744-22-5) is a chemical compound with molecular formula C8H5F3N2OS and molecular weight 234.00746 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
Also Known As: riluzole, Rilutek, Riluzol, Riluzolum, Tiglutik
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H5F3N2OS |
| Molecular Weight | 234.00746 g/mol |
| XLogP | 3.6 |
| Topological Polar Surface Area (TPSA) | 76.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 1 |
| Exact Mass | 234.00746 Da |
| Heavy Atoms | 15 |
| Complexity | 238.0 |
| Melting Point | 119 |
| Solubility | 3.95e-02 g/L |
| SMILES | C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N |
| InChIKey | FTALBRSUTCGOEG-UHFFFAOYSA-N |
Product Description
Applications: Riluzole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Riluzole (CAS 1744-22-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Riluzole (CAS 1744-22-5) has the molecular formula C8H5F3N2OS and a molecular weight of 234.01 g/mol. Reported properties include a solubility: 3.95e-02 g/L. It is also known as riluzole and Rilutek.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Riluzole
Property Insights of Riluzole
The XLogP value of 3.6 indicates that Riluzole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Riluzole. Following Lipinski's Rule of Five, Riluzole has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Riluzole?
The CAS number of Riluzole is 1744-22-5.
What is the molecular formula of Riluzole?
The molecular formula of Riluzole is C8H5F3N2OS.
What is the molecular weight of Riluzole?
The molecular weight of Riluzole is 234.00746 g/mol.
What are the applications of Riluzole?
Riluzole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Riluzole (CAS 1744-22-5) with custom synthesis...
Where can I buy Riluzole?
You can request a quote for Riluzole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Riluzole?
Yes, CoreyChem provides custom synthesis services for Riluzole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.