Tegafur
TL;DR: Tegafur (CAS 17902-23-7) is a chemical compound with molecular formula C8H9FN2O3 and molecular weight 200.05972 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione
Also Known As: tegafur, Ftorafur, Futraful, Sinoflurol, Fental
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H9FN2O3 |
| Molecular Weight | 200.05972 g/mol |
| XLogP | -0.3 |
| Topological Polar Surface Area (TPSA) | 58.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 200.05972 Da |
| Heavy Atoms | 14 |
| Complexity | 316.0 |
| Melting Point | 339.8-343.4 |
| Solubility | Partly miscible |
| SMILES | C1CC(OC1)N2C=C(C(=O)NC2=O)F |
| InChIKey | WFWLQNSHRPWKFK-UHFFFAOYSA-N |
Product Description
Applications: Tegafur is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Tegafur (CAS 17902-23-7) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Tegafur is a pharmaceutical intermediate identified by CAS number 17902-23-7 and the molecular formula C8H9FN2O3 and a molecular weight of 200.06 g/mol. Physically, the compound has a solubility: Partly miscible. It is also known as tegafur and Ftorafur.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Tegafur
Property Insights of Tegafur
The XLogP value of -0.3 indicates that Tegafur is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 58.6 Ų, Tegafur exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tegafur has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tegafur?
The CAS number of Tegafur is 17902-23-7.
What is the molecular formula of Tegafur?
The molecular formula of Tegafur is C8H9FN2O3.
What is the molecular weight of Tegafur?
The molecular weight of Tegafur is 200.05972 g/mol.
What are the applications of Tegafur?
Tegafur is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Tegafur (CAS 17902-23-7) with custom synthesis...
Where can I buy Tegafur?
You can request a quote for Tegafur directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tegafur?
Yes, CoreyChem provides custom synthesis services for Tegafur and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.