TL;DR: Prazosin Hydrochloride (CAS 19237-84-4) is a chemical compound with molecular formula C19H22ClN5O4 and molecular weight 419.13602 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone;hydrochloride
Also Known As: Prazosin hydrochloride, Prazosin HCl, Minipress, Peripress, Vasoflex
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
| Molecular Formula | C19H22ClN5O4 |
| Molecular Weight | 419.13602 g/mol |
| XLogP | 2.21 |
| Topological Polar Surface Area (TPSA) | 107.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 419.13602 Da |
| Heavy Atoms | 29 |
| Complexity | 544.0 |
| Melting Point | Crystals. MP: 278-280 °C /Prazosin/ |
| Solubility | Soluble at ambient temperatures (mg/ml): acetone, 0.0072; methanol, 6.4; ethanol, 0.84; dimethylformamide, 1.3; dimethylacetamide, 1.2; chloroform, 0.041 |
| SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC.Cl |
| InChIKey | WFXFYZULCQKPIP-UHFFFAOYSA-N |
The XLogP value of 2.21 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Prazosin Hydrochloride. The TPSA of 107.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Prazosin Hydrochloride. Following Lipinski's Rule of Five, Prazosin Hydrochloride has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of Prazosin Hydrochloride is 19237-84-4.
The molecular formula of Prazosin Hydrochloride is C19H22ClN5O4.
The molecular weight of Prazosin Hydrochloride is 419.13602 g/mol.
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